This approach may lead to a beneficial misclassification regarding BP classes and you may expose dilution prejudice, perhaps underestimating true contacts

This approach may lead to a beneficial misclassification regarding BP classes and you may expose dilution prejudice, perhaps underestimating true contacts

In the current study, the association of new BP categories with risk of incident CVD was more evident in young adults aged <40 years than in the older subjects, which is in line with earlier studies that also reported a stronger association between BP and CVD outcomes in middle?aged compared with elderly populations. 8 , 46 , 51 , 52 , 53 The reasons for the stronger associations in young adults are unclear.

The outcome off BP toward chance of CVD may be toned down having broadening decades because both the incidence out of higher BP and you will most other CVD risk affairs in addition to be Web sitelerini ziyaret et much more common as we grow old

For the Southern Korea, the fresh new Korean Community of Blood pressure level calculated to use the last blood pressure standards from systolic BP/diastolic BP ? mm Hg due to insufficient obvious evidence for further benefit from reducing the blood pressure levels threshold so you can mm Hg having Koreans. 54 , 55 According to the Korean Blood circulation pressure Fact Sheet 2018, the number of some body identified as having blood pressure levels improved regarding step 3 million inside 2002 to 8.9 million within the 2016, in just 5.7 mil individuals with suitable and chronic antihypertensive medication in 2016. 56 The therapy price increased out of 22% in 1998 to help you 59% in 2007 and 61% inside 2016, together with control rate improved from 5% in 1998 to help you 41% inside 2007 and to forty-two% within the 2016. 56 From inside the research conducted recently making use of the Korean National Health and Diet Test Survey, the fresh new incidence of blood pressure level while the amount of people who need antihypertensive treatment would-be enhanced, getting equivalent along with other regions. 55 , 57 , 58 According to current knowledge dealing with utilization of this new guidelines during the numerous places, including the You, Asia, and you may Korea, the fresh 2017 ACC/AHA blood circulation pressure guidance often markedly enhance the prevalence of blood pressure level and you will exactly how many clients who are in need of antihypertensive medication initiation and the ones who require therapy intensification around the world. 57 , 58 , 59 , 60 , 61 , 62 When you look at the research conducted recently in the National Health and Nourishment Examination Survey, with regards to the 2017 ACC/AHA guideline, compared with the new 7th Mutual Federal Panel rule, this new frequency off hypertension has grown regarding 31.9% so you can forty-five.6%, the brand new portion of United states adults suitable for antihypertensive medication has increased off 34.3% in order to thirty six.2%, and you can 53.4% of us adults taking antihypertensive therapy you prefer alot more rigorous lowering of their BP. 59 In the eventuality of Asia, adoption of your own 2017 ACC/AHA hypertension recommendations would resulted in increment on the frequency regarding hypertension of 25% to 50%. 63 It should be analyzed in the event that such as for instance alterations in this new diagnostic endurance and you may therapeutic plans off to help you mm Hg create raise BP handle as well as relevant consequences. Future research is including needed seriously to confirm the latest organization between BP and you will CVD chance about more youthful populace which have diverse ethnicity and you may to decide if the exposure/work with proportion to own treatment solutions are favorable within this low?risk category.

Age and you may intercourse standardization is performed utilizing the direct means to your ages build of one’s Korean populace, aged 20 in order to 80 age, around 2010

The strengths of our study are its cohort study design, the large sample size, the use of carefully standardized clinical procedures, and the almost complete follow?up for CVD events, as the National Health Insurance collects all medical services use covering the entire Korean population. This study also has several limitations. First, as with most previous studies, the determination of BP was based on a single?day measurement, although 3 readings were taken. Second, we did not incorporate changes in BP categories and other covariates during follow?up. Third, health behaviors were assessed via a self?administered structured questionnaire used in health checkup programs in Korea, as part of the National Health Insurance plan. Measurement errors in these variables may introduce some degree of residual confounding, similar to most epidemiologic studies. Fourth, we used the Pooled Cohorts Equations in all participants; however, it was not validated in adults aged <40 years. Finally, this is an opportunistic cohort of individuals, who self?presented for the health examination, and hence is not a representative sample of low cardiovascular risk young adults in the community. The study population of this cohort was relatively highly educated, young to middle?aged Korean adults with high accessibility to healthcare resources. We compared our study population with a representative sample of the general Korean population (the Korea National Health and Nutrition Examination Survey). The age? and sex?standardized prevalence of hypertension (defined as systolic BP ?140 mm Hg, diastolic BP ?90 mm Hg, or the use of antihypertensive medication), type 2 diabetes mellitus (defined as fasting serum glucose level ?126 mg/dL or the use of blood glucose–lowering agents), obesity (body mass index ?25 kg/m 2 ), and current smoker was lower than those of the general population (16.6% versus 29.1%, 9.3% versus 10.5%, 27.6% versus 31.5%, and 16.8% versus 26.5%, respectively), indicating that our study population may be healthier than the general Korean population. Thus, our findings might not be generalizable to other ethnic groups or populations with different age, demographic, diet, and health behavior characteristics.


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